Herramientas para el análisis de mecanismos de resistencia de Candida albicans Academic Article

abstract

  • Candida albicans is a commensal yeast that is part of the human microbiota, but that in patientsImmunosuppressed can cause skin, subcutaneous and systemic infections. It has the ability to forma biofilm, through the production of extracellular polysaccharides that allows it to adhere to practically any type of surface, live in communities and evade the action of the immune system, considerably increasing its resistance to antimicrobial molecules compared to microorganisms in a free or planktonic state. Fluconazole and amphotericin b are the main drugs used against infection caused by this microorganism; however, resistance to these antifungals and other azoles is a problem.clinically important. This review highlights proteomics as an alternative tool for the analysis of the resistance mechanisms of C. albicans.

publication date

  • 2018/5/1

edition

  • 38

keywords

  • albicans
  • biofilm
  • commensal
  • microbiota
  • resistance
  • surface

International Standard Serial Number (ISSN)

  • 1405-0994

number of pages

  • 6

start page

  • 86

end page

  • 92