Caracterización de pacientes adultos mayores con epilepsia en dos hospitales en Bogotá, Colombia Thesis

short description

  • Postgraduate thesis

Thesis author

  • Gutiérrez-Álvarez, Ángela-María
  • Ortíz Salas, Paola
  • Palau Pérez, Luis David
  • Quintero Cusguen, Patricia
  • Sobrino Mejía, Fidel
  • Velez-van-Meerbeke, Alberto
  • Vélez van Meerbeke, Alberto Francisco

abstract

  • IntroductionEpilepsy’s overall prevalence in Colombia is 1. 13%. Its prevalence in patients aged over 65 could be around 1. 5%. Little information is available about this pathology’s behaviour and treatment in this age-group. Materials & methodsA cross-sectional descriptive study was carried out in two high complexity hospitals in Bogotá, Colombia during 2005-2008. Demographic data were compiled and patients were characterised regarding the type, frequency and diagnosis of the crisis (based on ILAE classification), probable aetiology, having a family background of epilepsy, and current pharmacological management. Results211 clinical histories were reviewed and 179 of them selected. Mean patient age was 75 (65-98) and average age at onset of epilepsy was 67. 5 (7-93). 84% of the crises were classified as being partial. The most frequently occurring diagnosis was symptomatic focal epilepsy (94. 4%). 74 cases (41. 3%) had an aetiological diagnosis. The most important cause was cerebrovascular disease (61 patients). First generation anti-epileptic drugs were the most used ones (99%). 81/104 patients were found not to be free from epileptic episodes. ConclusionsMost seizures have a partial beginning, resulting from symptomatic partial epilepsy as a consequence of a vascular lesion. Pharmacological treatment must be considered following the first crisis. Treatment with second generation anti-epileptic drugs such as Lamotrigine, Gabapentin, Levetiracetam and Topiramate must be begun for minimising secondary effects and low doses must be maintained from the start of treatment. Costs may limit the use of the above antiepileptics, in such cases Phenytoin may be used with extreme caution.

publication date

  • March 15, 2010 10:23 PM

keywords

  • Elderly
  • Epilepsy

Document Id

  • 1ed94ce1-d0bf-4ff1-8cab-dcef6dd6f72b