Factores asociados a infección de vías urinarias por E. Coli y K. Pneumoniae con resistencia Blee. Estudio de casos y controles en una institución de salud con enfoque en el cuidado de la mujer
Thesis
Objective: To identify the factors associated with the generation of urinary tract infection produced by E. coli and K. pneumoniae with ESBL resistance in a health institution in Bogotá between January 2013 and April 2018. Materials and methods: Observational study, type cases and controls in women between 18 and 50 years of age with a diagnosis of urinary tract infection caused by Escherichia coli and Klebsiella pneumoniae, with ESBL-type resistance, who attended the emergency room and / or who were hospitalized. Results: 165 women, 55 cases and 110 controls were included; in the multivariate analysis it was found that the use of antibiotics in the last year (OR 17.44) p <0.00 and the days before the use of antibiotic (OR 0.98) p <0.00 were the significant variables. Discussion: Several factors have been associated with the presentation of E. coli and Klebsiella pneumoniae infections with ESBL resistance; but within the statistical models found the common factor is the use of previous antibiotics, it is at this point where the question posed, how long ago did the antibiotic use, becomes very important, since it was evidenced that in the case group the average it was 35 days, and in the control group it was 78 days. Conclusions: A very significant association was found with the use of antibiotics in the last year with an OR of 17,44, as with the previous days of antibiotic use, where at a shorter previous time of use, the risk is higher.
