Introduction: chronic renal failure CRF has increased its prevalence in recent years, from 44.7 patients per million in 1993 to 538.46 patients per million in 2010 patients, patients who receive renal replacement therapy hemodialysis in Colombia have increasingly improved survival. The increase in the number of patients and the increase in the survival encourage us to improve the quality of life for dialysis years.Methodology: The quality of life was compared by SF-36 in 154 patients with end-stage CRF on hemodialysis management, 77 incidents patients and 77 prevalent patients who are part of a renal unit in Bogota, Colombia.Results: It was found a decrease in the quality of life in the physical components (PCS) and mental (MCS) of hemodialysis patients in both groups. In the logistic regression model, the work disability (p = 0.05), catheter use (p = 0.000), low body mass index (p = 0.021), hypoalbuminemia (p = 0.033) and anemia (p = 0.001) were determinant factors in 78.9% poor quality of life in PCS in incident patients compared to prevalent ones. In MCS of incident patients vs. Prevalent patients was found hypoalbuminemia (p = 0.007), anemia (p = 0.001) and access by catheter (p = 0.001) as determinant factors in 70.6% of low MCS Conclusions: The quality of life of dialysis patients is affected with greater impact on the group of incident patients, the nutritional aspects should be enhanced, hematological and vascular access in this group.
