Asociación entre temperatura corporal al ingreso a urgencias y mortalidad intrahospitalaria en pacientes sépticos Thesis

short description

  • Master's thesis

Thesis author

  • Buitrago, Tatiana Patricia

abstract

  • Objective: To estimate the association between admission body temperature and in-hospital mortality in patients diagnosed with sepsis admitted to Salem Méderi Hospital Universitario Mayor between February and July 2017. Methodology: Analytical prospective cohort study between February and July 2017 of patients who were admitted to Salem, who were diagnosed with sepsis, taking their temperature at admission and in-hospital mortality was analyzed, adjusting to other independent variables. Results: 171 patients with a diagnosis of sepsis were analyzed, with a median age of 71 years (IQR 17). The most frequent septic foci were abdominal 38%, pulmonary 28. 1% and urinary 24. 6%. The incidence of normothermia, hypothermia, and hyperthermia was 59. 1%, 28. 7%, and 12. 3%, respectively. In-hospital mortality was 32. 2% and 49. 1% presented septic shock. The Relative Risk (RR) for in-hospital mortality according to hypothermia Vs Non-hypothermia is 1. 58 95% CI (0. 85 - 2. 84) p = 0. 056. The incidence of death in hypothermic patients is 4. 2 per 100 hospitalized patient days, compared with an incidence of death in non-hypothermic patients of 2. 6 per 100 hospitalized patient days; not being statistically significant (p = 0. 056). Conclusions: In the logistic regression model, the variables with the greatest significance for predicting in-hospital mortality were pulmonary focus, septic shock, septic foci other than urinary (abdominal and other foci), Gram negative rather than Gram positive typing. Hyperlactatemia lost its association when adjusted; on the other hand, neutrophilia was evidenced as a protective factor. In this cohort, no direct association was found between body temperature and in-hospital mortality; but there is a trend, although it is not statistically significant between presenting hypothermia and mortality. The mortality of this population is substantially high.

publication date

  • October 4, 2018 8:54 PM

keywords

  • Critical care
  • Fever
  • Mortality
  • Sepsis
  • Shock septic

Document Id

  • 9d029858-6629-4656-ba4e-23512453dccc