Introduction: Parkinson's disease is a common neurodegenerative disorder and has been associated with occupational exposure to pesticides. The onset of symptoms of this disease is typically insidious; biological models suggest that disease progression includes a long presymptomatic period. It has currently been suggested that the development of Parkinson's disease is due to an interaction between genetic susceptibility and exposure to environmental factors, the latter being the most representative. Objective: To determine the relationship between the use of insecticides and the development of Parkinson's disease through a review of the literature from 2011 to 2021. Materials and methods: A scoping review of the literature will be carried out in the PUBMED, COCHRANE and GOOGLE SCHOLAR databases, in English and Spanish between 2012 and 2022, using keywords parkinson, insecticides, workers, occupational health. Results: It was observed that people who work mainly in agriculture had a higher prevalence of Parkinson's disease in populations with a high density of permanent crops and with direct exposure, but risks have also been described in domestic use and with the intake of water contaminated with these chemicals. In the same way, the appearance of clinical signs corresponding to Parkinson's disease at an early age is described. It was evidenced that the intensity and time of exposure to insecticides was associated with an increased risk of suffering from Parkinson's disease.
