Alta tasa de afectación cardiaca en pacientes colombianos con enfermedad de Kawasaki Academic Article

abstract

  • Kawasaki disease (KD) is a systemic vasculitis, whose main complication is the coronary arteries involvement. This was a retrospective study in which 48 Colombian KD patients were included, and the rate and associated factors to cardiac involvement were investigated. The mean time from the first symptom until the diagnosis was 10.5 days. Cardiac involvement was registered in 13 (27%) patients, of whom 10 presented with coronary disease and 3 with a different cardiac manifestations. Forty-one patients (85.4%) received IV immunoglobulin. By multivariate analysis, the patient's age (OR: 0.91, 95% CI: 0.85-0.98, p = 0.01) and the lapse of time between onset of symptoms and diagnosis (OR: 1.21, 95% CI: 1.05-1.41, p = 0.01) were associated factors influencing cardiac involvement and coronary disease, respectively. The high rate of cardiac compromise in Colombian patients agrees with that observed in other Latin American populations.

publication date

  • 2009/6/1

edition

  • 16

keywords

  • Coronary Disease
  • Coronary Vessels
  • Heart Diseases
  • Intravenous Immunoglobulins
  • Mucocutaneous Lymph Node Syndrome
  • Multivariate Analysis
  • Population
  • Retrospective Studies
  • Systemic Vasculitis

International Standard Serial Number (ISSN)

  • 0121-8123

start page

  • 132

end page

  • 137