Introduction: In Colombia the colorectal cancer is the fourth cause of death from cancer. The colonoscopy is a strategy for screening that helps to prevent pre-cancerous lesions. It is important to characterize clinically and endoscopically in our environment the success of this procedure. Objective: Characterize clinically and endoscopically all HUS patients who have received a colonoscopy from June 2017 to June 2018. Materials and Methods: Observational descriptive study of HUS patients which got a colonoscopy procedure at HUS from June 2017 to June 2018. Results: The results include a total of 554 colonoscopies. The gender distribution was similar between men and women and the age average was 57 years. In the 90% of the colonoscopies the Boston scale was reported to be achieved. In the 90% of the colonoscopies the cecum was visualized. The adenomas detection rate was 8,7%. The time needed to remove them was equal or greater 6 minutes in the 90% of the cases. The colorectal tumor rate was 6,3%. Conclusions: The proportion of success of the quality indicators with respect to the national standard was good on the order of frequency with which informed consent was obtained and fully documented and the percentage of the colonoscopies that the cecum was visualized. The adenomas and colorectal tumors rate detection rate was lower compare to Colombia national rate.