Loxoscelism is a disease caused by the bite of Loxosceles spider genus, which can generate cutaneous, systemic compromise and even death. The geographical distribution of spiders is worldwide, with the highest incidence in countries like Peru, Chile and Brazil, and even in some places in North America. In Colombia, we have identified this type of arachnid, but there are no cases of loxoscelism reported, we believe that probably they are under recorded. The clinical presentation can range from asymptomatic patients to severe dermonecrosis with a high risk of sequelae and functional disability. When there is systemic involvement this can be presented as renal failure, hemolysis, disseminated intravascular coagulation and high risk of death. Diagnosis is mainly clinical and epidemiological because there is no commercially available serological tests.Multiple treatment options have been described, however, there is no consensus to make recommendations, due to the limited scientific evidence. This article presents a literature review and case study of an 11 year old boy, with pitting of an unknown animal that presents dermonecrosis and multiorgan involvement with a suspicion of cutaneous and systemic loxoscelism. He was treated with antiarácnido serum, hyperbaric oxygen, an inhibitor of polymorphonuclear and surgical management with resolution but with sequels. We discuss diagnosis, underreporting and treatment of this entity in Colombia. The article seeks to promote knowledge of loxoscelism, to encourage greater clinical suspicion, early diagnosis, more accurate and timely in such accidents approach.
