Autoclinimetría aplicada colectivamente en pacientes Latinoamericanos con Artritis Reumatoide Thesis

short description

  • Postgraduate thesis

Thesis author

  • Amaya-Amaya, Jenny-Carolina
  • Anaya, Juan-Manuel
  • Botello Corzo, Diana
  • Calderón, Rolando
  • Calixto, Omar
  • Cruz-Tapias, Paola
  • Dominguez, Aura María
  • Mantilla, Rubén D.

external tutor

  • Rojas-Villarraga, Adriana

abstract

  • To apply therapeutic regimens such as tight control therapy in patients with rheumatoid arthritis (RA), is necessary to have objective measures of disease activity. For this reason clinimetry tools have created. Some of them are developed with measurements made by the doctor, like the DAS28, SDAI and the CDAI. Other trough self-administered questionnaire as the RAPID index, from the questionnaire R808-NP2 Spanish, or the self-assessment joint count using the SAI-form. There are some doubts about the validity of the questionnaire R808-NP2-Spanish, in patients of Hispanic origin.Objective: To evaluate the degree of association between the Rheumatoid Arthritis activity measures developed through self-assessment tools (R808 - Np2- Spanish questionnaire and SAI scheme), with those developed depending on physician and laboratory measures (DAS28 CRP 3V, 4V DAS 28 CRP, SDAI and CDAI), when those tools are applied collectively to a group of Latin American patients with Rheumatoid Arthritis. Methods and Results: This was a cross sectional study. 130 patients with RA were analyzed, using the RAPID, the DAS28PCR the CDAI and SDAI. Shared variability were greater than 50% between RAPID and SDAI and CDAI (p <0.0001); a kappa index of 0.76, 0.74 and 0.61 between DAS28 and RAPID PCR 4V 3, 4 and 5 (p <0.000), a kappa of 0.54, 0.57 and 0.69 between the CDAI and RAPID 3, 4 and 5 (p <0.000) and a kappa of 0.49, 0.50 and 0, 63 between the SDAI and RAPID 3, 4 and 5 (p <0.000).Conclusion Hispanic origin does not seem to impair the validity of the RAPIDs to evaluate RA disease activity index.

publication date

  • November 29, 2012 2:27 PM

keywords

  • CDAI
  • DAS28
  • Disease severity Index
  • Hispanic Americans.
  • MDHAQ
  • RAPID
  • Rheumatoid Arthritis.
  • SAI
  • SDAI

Document Id

  • 4316d0f7-b4a0-4d5d-a746-96ec9e611027