Background: Characterization of adverse effects related to intravenous opioids for acute pain in the elderly population is sparse in the literature. Objective: To map the evidence of adverse effects related to parenteral opioids for acute pain in elderly patients. Methodology: Scooping review of literature. The components of the research question were patients equal to or older than 65 years of age, description or analysis of adverse effects of parenterally administered opioids. Pain-related variables were taken into account. The outcomes associated with the adverse effect, the analysis or not of pharmacological interactions and sociodemographic variables such as race, social stratum, access to support network and history of opioid use were identified. We searched PUBMED, COCHRANE, EMBASE, Scopus and gray literature databases, without any language restriction. Results: Thirty-five studies were obtained. The country that reported the most was the United States (40%). The most frequently formulated opioid was phenatnyl in 42% of the studies (n=15). The most frequently encountered adverse effect were those related to the gastrointestinal tract in 37% of the articles. The most frequently associated comorbidities were cardiovascular. The sociodemographic stratum of the patients was reported in 5.71% (n=2). Conclusion: A description of the number, types of studies, outcomes, type of population, and adverse effects related to parenteral opioids for acute pain in patients aged 65 years or older was presented.
publication date
July 27, 2021 12:20 AM
Research
keywords
Adverse effect in the use of opioids in the treatment of pain
Analysis of side effects in the treatment of acute pain with opioids in the elderly
Frequency of presentation of side effects compared to the administration of intravenous opioids
