Pronóstico neurológico según la variabilidad de la frecuencia cardiaca en neonatos con encefalopatía Hipóxico-Isquémica sometidos a protocolo de hipotermia. Revisión de alcance
Thesis
Background: Hypoxic-ischemic encephalopathy (HIE) is one of the main pathologies in the neonatal population, it generates high morbidity and mortality and high costs to the health system. The neurological prognosis is variable, and studies have shown improvement in patients with heart rate variability undergoing hypothermia. Objective: Describe the evidence in relation to heart rate variability in the use of hypothermia protocols in neonates with HIE and its impact at the neurological level. Methodology: An exploratory systematic review was carried out, which included analytical and descriptive secondary, intervention and observational studies with primary data that will address the use of the hypothermia protocol in neonates with HIE and how cardiac variability was associated with neurological prognosis. Results: Through the exploratory systematic review, 2,508 articles were found, of which 6 studies were included by screening and selection, with a total population of 356 neonates, diagnosed with HIE, subjected to hypothermia protocols and evaluated in neurological outcomes by means of imaging and electroencephalogram (EEG), where the results were favorable for the majority of the population and exploring the associations of heart rate variability (HRV) it is evidenced that there is a probable association between lower variability with worse neurological prognosis. Conclusions: There is uncertainty in the results regarding the association of HRV and neurological outcome, given that the included studies are of low quality of evidence.
publication date
August 5, 2021 5:57 PM
Research
keywords
Analysis of Heart Rate Variability (HRV) in Neonates Undergoing Therapeutic Hypothermia
Analysis of the neurological impact of Therapeutic Hypothermia
Hypothermia protocols in neonates with HIE and their impact at the neurological level
