Neurosensory hearing loss in the newborn is most frequently found with increasing risk factors. Taking into account risk factors and the application of Transient Otoacoustic Emissions (TOAEs) as a screening test, a case control analytic study was conducted with the objective of establishing statistical associations between risk factors and failed or absent otoacoustic emissions. The current study was conducted at the Hospital Universitario de la Samaritana with a sample of 192 newborn children with one or more risk factors for neurosensory hearing loss. Transient Otoacoustic Emissions were conducted in the whole simple; 176 of the newborn children passed the test and were considered the control group. The remaining 16 newborn children had absent responses constituting the case group. Using chi-squared test, risk calculation, and Fisher’s exact test we observed a lack of correlation between risk factors and failed otoacoustic emission responses.