Caracterización de hallazgos radiológicos pulmonares en fibrosis quística entre 2014-2022: Experiencia en Fundación Cardioinfantil Thesis

short description

  • Postgraduate thesis

Thesis author

  • Polania Mosquera, Albert Francisco

external tutor

  • Pérez Alvarado, María Carolina

abstract

  • Background: Cystic Fibrosis is a hereditary disease, with pulmonary manifestations which are the main cause of morbidity and early mortality. Diagnostic images play an important role in the follow-up of these patients, as it allows the evaluation of structural alterations even when they are asymptomatic. The present study evaluated the pulmonary radiological findings in patients with cystic fibrosis in two high complexity institutions. Methods: A cross-sectional descriptive study was performed. All patients diagnosed with cystic fibrosis between 2014-2022 at the Fundación Cardioinfantil and Fundación Neumológica Colombiana were included. We characterized the pulmonary findings on institutional X-rays and HRCT, a descriptive analysis was made. The prevalence was calculated taking into account all the kids who attended the neumologic pediatric ambulatory services. Results: The prevalence was <1%, 51 patients were analyzed, the median age at diagnosis of 2.05 years. There was a median of 9 radiographs, 2 CT scans, and 4 ultrasounds per patient. Bhalla scores worsened in 53.6% of patients during CT follow-up. Discussion: The findings obtained by CT showed a subtle worsening in half of the patients, demonstrating the progressive involvement of the disease, compared to previous control. The large dose of radiation they receive, due to the high number of studies carried out, is important to be taken into account during follow-up. Not least, in Colombia a late diagnosis is made compared to other countries, it is recommended to implement neonatal screening for early diagnosis.

publication date

  • July 16, 2022 12:25 AM

keywords

  • Chest x-ray
  • Computed tomography
  • Cystic fibrosis
  • Lungs
  • Radiology

Document Id

  • fdaded4d-9479-429f-892d-3d55a8daa044