Infectious aspects and the etiopathogenesis of rheumatoid arthritis Academic Article

journal

  • Clinical Reviews in Allergy and Immunology

abstract

  • Infections are believed to contribute to the maturation of the immune system from the innate to the adaptive phases and therefore may take part in the induction of autoimmune conditions. In the current study, we present an extensive analysis conducted on sera samples of patients with rheumatoid arthritis in order to seek evidence of previous or coexisting infectious processes using the Bio-Rad BioPlex immunoassay analyzer. We detected higher rates of serological evidence of infections with Epstein-Barr virus and cytomegalovirus viruses. Our findings may indicate a role of these viruses in the pathogenesis of RA. © Humana Press Inc. 2009.

publication date

  • 2010/4/1

keywords

  • Cytomegalovirus
  • Epstein-Barr Virus Infections
  • Immune System
  • Immunoassay
  • Infection
  • Rheumatoid Arthritis
  • Serum
  • Viruses
  • bioplex

International Standard Serial Number (ISSN)

  • 1080-0549

number of pages

  • 5

start page

  • 287

end page

  • 291