Duckeodendron cestroides is the sole species in Duckeodendraceae and has also been included in Solanaceae. Boraginaceae and Apocynaceae. Analysis of rbcL sequence data indicates a placement within Solanaceae, within which Duckeodendron appears to be an isolated taxon, falling in a paraphyletic grade that also includes Goetzea, Metternichia, Schizanthus, Schwenckia and Salpiglossis. The molecular results are discussed in the light of the morphological and anatomical characters of Duckeodendron and other Solanaceae.