Patentometrics studies in middle-low-income countries is an emergent field. This study aims to unveil the inventive structure of Colombia from 1983-2021 as a pilot case. Applying the co-word analysis network analysis to the IPC (International Patent Classification) subclasses of 2,900 patents granted to inventors/applicants with Colombian affiliation/origin, we constructed the inventive network for three periods 1983-2000, 2001-2010, 2011-2021, and detected highly strategic IPC subclasses. Furthermore, we identify the structural changes by IPC sections and highlight the clustering properties of IPC sections for Colombia, such as C-Chemistry, metallurgy; A-Human necessities; B-Performing operations, transporting; G-Physics; and F-mechanical engineering, lighting, heating, weapons, blasting.