Características tomográficas y de función pulmonar en adultos con Covid-19 severo durante la infección y un año después Thesis

short description

  • Master's thesis

Thesis author

  • Carmona Montilla, Natalia Andrea
  • Lanziano Lobo, Keyla Manuela
  • Vargas Vargas, Marcela

abstract

  • Introduction: By the end of 2019, the first cases of rapid-progression pneumonia began to be diagnosed, at the time of unknown etiology (1), with subsequent studies it is possible to determine by radiological and microbiological characteristics of viral origin, pathogen of the Coronaviridae family (SARS-CoV-2) (2). Objectives: Compare the tomographic and pulmonary function characteristics in adults with severe COVID19 during the infection and a year later. Methodology: Observational study, in two centers, of historical cohort, of adult patients over 18 years of age with documented and confirmed infection by COVID-19 who were hospitalized or admitted to the Intensive Care Unit (ICU) during the period from March 2020 to October 2021 at the Central Hospital of the National Police and the Hospital of San José. Results: The sample studied corresponds to 113 patients, of which 88.5% received care at the Central Hospital of the National Police; 60.2% of the total sample corresponds to the male gender, with a minimum age of 25 years and a maximum of 94 years. The results indicate that there are statistically significant differences between the presence of consolidation, frosted glass and percentage of pulmonary involvement measured in time 0 and the year of follow-up with a p < 0.001. 83.18% of the cases did not present pulmonary involvement per year of follow-up on tomography, however, 47.87% (45) if they presented spirometric alterations. Discussion: Radiological changes similar to fibrotics persisted in 3.53% of the sample, demonstrating the resolution of most of the tomographic patterns evidenced during acute COVID 19 infection, despite not having tomographic alterations, in spirometry 47.87% presented pulmonary involvement, mostly restrictive pattern.

publication date

  • August 5, 2024 7:38 PM

keywords

  • Coronavirus
  • Covid 19
  • Fibrosis
  • Pandemic
  • Severe pneumonia

Document Id

  • af1bce95-edba-48b3-af9a-8b3d3be3bcf2