Anemia aplastica. Tratamento alternativo a transplantacao medular Academic Article

•  
• Overview
•  
• Research
•  
• Identity
•  
• Additional Document Info
•  
• View All
•  

Overview

journal

• Acta Medica Portuguesa

abstract

• We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed.

authors

• Gómez Giraldo, Beatriz Lucía
• J. J.G. D'Oliveira
• J. M. Forjaz De Lacerda
• J. Raposo
• T. Fonseca

publication date

• 1997-1-1

edition

• 10

Research

keywords

• Adrenal Cortex Hormones
• Antilymphocyte Serum
• Aplastic Anaemia
• Bone Marrow Transplantation
• Cyclosporine
• Immunosuppressive Agents
• Intercellular Signaling Peptides and Proteins
• Siblings
• Therapeutics
• Tissue Donors

Identity

International Standard Serial Number (ISSN)

• 0870-399X

Additional Document Info

number of pages

• 4

start page

• 99

end page

• 102