Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy Academic Article

journal

  • Clinical and Vaccine Immunology

abstract

  • We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall specificity was 94%. The antigen test successfully monitored the response to therapy.

publication date

  • 2014-9-1

edition

  • 21

keywords

  • Acquired Immunodeficiency Syndrome
  • Antigens
  • Assays
  • Enzyme-Linked Immunosorbent Assay
  • Enzymes
  • Histoplasma
  • Histoplasmosis
  • Immunosorbents
  • Therapeutics

International Standard Serial Number (ISSN)

  • 1556-6811

number of pages

  • 5

start page

  • 1364

end page

  • 1368