Monitoring sepsis using electrical cell profiling in a mouse model
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We developed double-sided iso-dielectric separation system for monitoring sepsis progression using electrical characterization of leukocyte activation. With inertial sorter integration, we can characterize the electrical properties of leukocytes from ampersand-flag-changesim; 50 ampersand-flag-changemu;L sample of whole blood within 15 minute. In the end, we quantify leukocyte activation in a mouse sepsis model, representing the first use of electrical cell profiling to provide a clinically relevant metric.
