Susceptibility to rubella infection in females at high risk. Immune protection associated to population density Academic Article

journal

  • Tropical and Geographical Medicine

abstract

  • Susceptibility to rubella in 428 Mexican females of childbearing age from four sanitary areas confined to a Mexican State (Queretaro) was determined. Members of the group were residents of urban and rural communities and selected by random sampling. Anti-viral antibodies were determined by inhibition of haemagglutination. Concentration was expressed as International Units of IgG anti-rubella haemagglutinin (IU/ml). Antibody concentrations lower than 15.6 (IU/ml) were regarded as non-protective. The percentage of women immune-protected to rubella in the areas varied from 28.8 to 75.6 with an average of 61.9. The difference in percentages of immune-protected females within the areas was statistically significant (ampersand-flag-changechi;2 = 48.26 and p ylt; 0.001). Immune protection was associated to population density, with less protection in less populated areas. Our results differ from the reported values of a serosurvey performed in the same state one year before: immune protection 61.9percent-flag-change versus 79.96percent-flag-change, respectively.

publication date

  • 1995-1-1

edition

  • 47

keywords

  • Anti-Idiotypic Antibodies
  • Antibodies
  • Group
  • Hemagglutination
  • Hemagglutinins
  • Infections
  • Population Density
  • Rubella
  • Rural Population
  • Viral Antibodies
  • anti-IgG
  • antibodies
  • hemagglutination
  • hemagglutinins
  • infection
  • population density
  • resident
  • rural communities
  • rural community
  • sampling
  • viral antibodies

International Standard Serial Number (ISSN)

  • 0041-3232

number of pages

  • 4

start page

  • 235

end page

  • 238