PURPOSE: To describe demographic data, clinical features, and serological profiles in a cohort of Congolese patients with ocular toxoplasmosis (OT).METHOD: Cross-sectional study, carried out between March 2020 and July 2021 in two ophthalmic clinics in Kinshasa.RESULTS: The study comprised 95 participants with OT. Fifty-three patients were male (55.8percent-flag-change). The mean age at presentation was 35.6 ampersand-flag-changeplusmn; 14.1 years (range 8-69 years); 71 had active OT (74.7percent-flag-change), among them, 33 had primary OT (46.5percent-flag-change), and 38 had recurrences (53.5percent-flag-change). At presentation, 51 patients (53.7percent-flag-change) had visual impairment (VA ylt; 6/18). Retinochoroidal lesions were located in the central retina in 60 patients (63.1percent-flag-change). Patients with primary OT tend to have higher IgG levels than those with recurrent OT ( P = .01). CONCLUSION: We report the largest cohort of patients with OT in sub-Saharan Africa. In our setting, most patients had recurrent OT with multiple, extensive, and central retinochoroidal lesions.
