A 67-year-old woman, with a history of diabetes mellitus, hypertension, deep vein thrombosis in the right lower limb, was admitted to the Mastology Department at HUMM due to a sensation of a mass in the left breast that had been present for a year. On physical examination revealed a poorly defined mass in the left breast, coordinate 10.1. Ultrasound report Bi-rads 4C moderate suspicion of malignancy given by circumscribed oval nodule time 10, 1 cm measuring 24 x 17 x 15 mm and Bi-rads 0 mammography. The pathology of the initial trucut biopsy reported atypical stromal and fusocellular proliferation of difficult classification of nature and biological behavior to be defined by immunoperoxidases, which favored myofibroblastoma, extension studies were negative. Conservative surgery was performed with quadrantectomy with harpoon marking guided by ultrasound. The patient did not receive additional treatment or medication. Clinical and imaging follow-up showed no signs of tumor recurrence. CONCLUSION: Given its presentation as an unusual variant in women (2), this case provides information on the imaging and histological diagnosis and surgical treatment of a case of myofibroblastoma of the breast.
