The clinical presentation of breast cancer is highly variable; most tumors are located in the upper outer quadrant of the breast, followed by the upper inner, and the lower outer. The internal lower quadrant and the central-mammary region are the least frequent sites as reported in the literature (1). A case of breast cancer in the inter-mammary region of a patient treated at the Mayor Méderi University Hospital (HUMM) is presented. Case report: A 63-year-old woman, with no significant history, who was admitted to the HUMM Mastology clinic due to a sensation of a mass located in the inter-mammary region, with progressive growth in the last 6 months. On physical examination, a 2 cm mass was identified in the intermammary region without skin involvement. Report of breast ultrasound and mammography BIRADS 2: Benign findings. The pathology reported hypercellular mucinous carcinoma, 100% positive estrogen receptors, 75% positive progestin receptors, HER2 negative by FISH, KI67: 20%, Luminal B. Magnetic resonance imaging shows an irregular mass with marked enhancement in the inter-mammary valley, without lesions. defined in breasts. The extension studies were negative and it was staged as cT2N0M0, Stage IIA. Conservative surgery with quadrantectomy and bilateral sentinel node was performed due to radiocolloid migration to bilateral lymph node groups after peri-tumoral application. Patient received hormonal therapy with tamoxifen and adjuvant radiotherapy. Clinical and imaging follow-up shows no signs of local relapse. Conclusion: This is the second case of intermammary localized breast cancer reported in the literature (2). Given the strange location, this report provides information as an alternative management in patients with similar characteristics
