Introduction: Heart transplantation is an option that is well supported by evidence to consider in patients with advanced heart failure. Objective: To determine the clinical characteristics of the population that underwent the first heart transplant at the Fundación CardioInfantil during the period 2005-2022 and to evaluate whether there is a difference in percentage for the predicted size of ventricular mass between donor and recipient of heart transplant compared to the percentual difference in body weight between these same groups. Methods: This will be an observational, cross-sectional, analytical study. Results: Between 2005-2022, information was collected from 92 patients receiving a CT scan along with the respective donor data, with a median follow-up of 38.8 months, with an all-cause mortality rate of 17.4%. Weight-matching was documented in 20.6% of patients with a median age of 44 years and weight of 64.7 kg. Most of these patients were men and had a mortality at one-year follow-up of 15.8%. According to predicted heart mass matching, the distribution found was paired 13.0% lower than the recipient, 65.2% greater than the recipient, the matched group had an average matching of 17.3% and the one-year mortality rate was much lower than the other two groups, at 1%.
