RationaleSevere sepsis of abdominal origin is the second leading cause of ICU admission in Colombia with 30% mortality, so it is necessary to determine clinical factors associated with torpid for identification and early management and determining prognosis.Material and methods We conducted a case-control study of patients admitted to ICU with a diagnosis of abdominal sepsis. He described the quantitative and qualitative variables and logistic regression was performed to establish significant variables associated with the treatment failure, defined as mortality.ResultsWe included 235 patients, 62 cases and 173 controls, mean age 58 years, mostly men. The most common source of infection was gastrointestinal, liver and biliary tract. Was observed SOFA and APACHE II higher in patients who died, as well as shock and SIRS persistence at 96 hours of monitoring. In logistic regression, the following variables were associated with treatment failure: age, renal failure (OR 3.19, p 0.003), cardiovascular complications (OR 2.3, p 0.029), coagulator (OR 3.57, p 0.001, and the presence of Enterococcus spp (OR 10.5, p 0.004).ConclusionsThe population described in the previous work has characteristics similar to that found in the literature. The variables associated with treatment failure found, not previously described, especially renal and cardiovascular failure, and the presence of Enterococcus spp, allowing establish them as risk factors associated with mortality in these patients, to medical and surgical interventions early.
