Background: The definition of stress as “Nonspecific answer of the system against any exterior demand” was presented at the World Health Organization (WHO) by Hans Selye; burnout syndrome is considered a complication derived from stress, a term introduced in 1970 by Freudenberger. Many studies have found the syndrome in healthcare personnel, even during the training process. Materials and methods: Population in this study are residents of medical and surgical specialties from the programs offered at Universidad del Rosario, using the Maslach Burnout Inventory in its Spanish version. Results: 236 subjects completed the evaluation, with an average age of 28 years (DE 2. 25), 41burnout Syndrome was found in 43. 6% of subjects, risk of developing the syndrome in 24, 6%, and burnout was not present in the remaining 31. 8%. Burnout syndrome was found in a higher proportion in subjects with: age less than 25 years 75% (p=0. 001), male gender 43. 8% (p=0. 01), single marriage status 43. 7% (p=0. 04), surgical specialization 56. 8% (p=0. 001). Conclusions: There are differences in burnout distribution between residency programs, Structured strategies to approach this pathology and prevent its occurrence are required. There is a clear association between burnout syndrome and some risk factors as: male gender, single marriage status, surgical specialization and hours of work per week during the residence, the last one having the strongest association in the statistical analysis.