Objective: To determine if there is a relationship between working conditions and family functionality in Colombia. Material and Methods: Cross-sectional study using the 2015 National Mental Health Survey. Family APGAR and the following working conditions were considered: salary, contract, type of entailment, hours worked per week and social security affiliation. Frequency analysis, Chi-Square and logistic regression were performed. Results: The family functionality is better in those who have an indefinite term contract when comparing them with those who do not have a contract (OR: 1.30, IC95%: 1.07-1.57), who belong to the contributory regime when compared them with the subsidized one (OR: 1.39, IC95%: 1.19-1.63), who earn more than two minimum wages when compared to those who earn less than half wage (OR: 1.86, IC95%: 1.44-2.40), who work between 25 and 48 hours/week when compared to those who work more than 48 hours/week (OR: 1.08 IC95%: 1.02-1.15). Conclusion: There is a relationship between working conditions and family functionality in the Colombian population.