Síntesis de puntos de carbono y revisión de su citotoxicidad en tumores de mama Thesis

short description

  • Undergraduate thesis

Thesis author

  • Barrera Olguin, Sttifany Marcela

external tutor

  • Ramírez Clavijo, Sandra Rocío
  • Ramírez-Clavijo, Sandra
  • Rodríguez Burbano, Diana Consuelo

abstract

  • This thesis work consists of the sintering of the carbon points, discovered in 2004 where they are described as carbon-based nanoparticles, these are characterized by possessing fluorescent properties sensitive to the environment in which they are found; in order to be used as luminescent probes for obtaining images on a cellular scale by fluorescence. Additionally, the therapeutic effect of a drug in a cancer cell line can be studied using the fluorescent properties of the carbon spots and taking advantage of the functional groups present on the surface of the carbon spot, then building a teranostic agent on a nanometric scale. However, it is necessary to evaluate the impact of carbon spots on cell lines, before integrating any therapeutic agent in order to determine possible intrinsic cytotoxic effects to these nanoparticles through a literary review.

publication date

  • May 29, 2020 8:08 PM

keywords

  • Carbon Dots
  • Cytotoxicity
  • Fluorescence
  • Synthesis

Document Id

  • bda30298-5f0b-4110-b2b4-992b66f0f851