Desenlaces según la caracterización fenotípica en lactantes con bronquiolitis aguda en la Clínica Infantil Colsubsidio en el 2019 Thesis

short description

  • Postgraduate thesis

Thesis author

  • Abella Morales, Diana María
  • Bustos Sánchez, Juan David

external tutor

  • Albarracín Bohórquez, Juan David

abstract

  • Introduction: Bronchiolitis is a highly prevalent disease of infectious origin that affects children under 2 years of age (2). Recommendations for intervention in patients with bronchiolitis over time has been limited to supportive management (2, 3, 8). However, in 2016, phenotypes were described in order to categorize patients and to propose more targeted therapies (8, 34, 35). The objective of this study is to describe the phenotypic classification of patients with bronchiolitis at the Colsubsidio Children's Clinic in 2019 and to evaluate the different interventions that were performed on them.Methods: A retrospective descriptive observational study was proposed, which included 1176 patients under 2 years of age with a diagnosis of bronchiolitis. Using the medical records for clasifying the patients in the diferent phenotypes, also we registered the intervention performed and the outcomesResults: The mean age of presentation of bronchiolitis was 4 months of age, with a predominance of the male gender. The main etiological agent was the respiratory syncytial virus (RSV). Phenotype B was the most prevalent with 45.5%. Phenotypes A and C were more associated with the use of bronchodilators, while phenotype C had greater severity.Conclusion: Taking into account the phenotypic classification of bronchiolitis, different treatments can be considered in patients with bronchiolitis that could have a favorable impact on their outcome. However, it is limited establishing phenotypes in a population with lack of clear clinical criteria that adequately distinguish them.

publication date

  • July 15, 2022 8:19 PM

keywords

  • Bronchiolitis
  • infants
  • phenotypes
  • respiratory syncytial virus

Document Id

  • d04edf38-e3b9-40ef-9111-7be60493a222