Outbreak of Wickerhamomyces anomalus (formerly Candida pelliculosa) Bloodstream Infections, Venezuela, 2022-2023 1 Artículo académico

Perfil
Identidad

Autor

Aleiram Chaurio-Briceño
Antoniellys Pérez-Guzmán
Bram Spruijtenburg
Diego H. Caceres
Eelco F.J. Meijer
Elaine Cristina Francisco
Jacques F. Meis
Juan F. Frey-Carrillo
Maribel Dolande-Franco
Rodrigo Oliveira
Tatiana Drummond-Suinaga
Yusely Roa-Díaz

Resumen

During August 2022-December 2023, a total of 110 bloodstream infections caused by Wickerhamomyces anomalus (synonym Candida pelliculosa) were identified across 8 hospitals in 3 cities in Venezuela. Most cases (82/110 in Caracas) occurred in a single pediatric intensive care unit, predominantly among neonates. Molecular genotyping indicated multiple events of clonal transmission, which was supported by epidemiologic clustering of patients. Antifungal susceptibility testing demonstrated good in vitro activity; most isolates were classified as wild-type. Our findings underscore the need for enhanced fungal diagnostics, infection prevention measures, and national surveillance to mitigate hospital-associated fungal transmission in resource-limited settings.

autores

http://vivoweb.org/ontology/core#FacultyMember
Ceballos Garzón, Carlos Andrés

fecha de publicación

2026-5-26

Área temática

Salud y bienestar

Edición

32

Número Internacional Normalizado de Publicaciones Seriadas (ISSN)

1080-6040

Identificador de objeto digital (DOI)

https://doi.org/10.3201/eid3206.251978