Standard deviations and correlations of GC levels in DNA sequences Academic Article

abstract

  • In a DNA sequence that exhibits long-range correlations, standard deviations among the GC levels of its segments can be up to an order of magnitude higher than in a sequence consisting of independent, identically distributed nucleotides. Conversely, plots of inter-segment standard deviations vs. segment length reveal quantitative information about the correlations present in a sequence. We present and discuss formulae that relate long-range (power-law) correlations between the nucleotides of a sequence to the expected standard deviations of the GC levels of its segments, and to the correlations between them.

publication date

  • 2001-10-3

edition

  • 276

keywords

  • Nucleotides

number of pages

  • 6

start page

  • 33

end page

  • 38