Positive benefit of postnatal treatment in congenital toxoplasmosis
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Overview
journal
BMJ
abstract
A well-established newborn screening programmefor congenital toxoplasmosis has beenreported in a European country with lowprevalence1; however, this programme has alsobeen implemented in countries with lowerincome but with a higher percentage of newborninfected children. We conducted a studyin 11 public health community hospitals in theDepartment of Quindio, excluding the capital(Armenia), in Columbia; about 4560 childrenare delivered in these hospitals annually.Infants born from August 2003 to December2003 were enrolled in the study. Informedconsent was obtained from mothers duringsampling and results were reported in accordancewith the resolution 008430 of 1993 ofthe Ministry of Public Health concerningmedical research in Colombia. All serumsamples were tested with the Platelia ToxoIgM Neonatal assay (Bio-Rad, Hercules,California, USA) as recommended by themanufacturer. In all, 322 samples were collected,including 106 dry paper samples fromthe heel, which about 25% of which wereinsufficient.
Un programa de detección de recién nacidos bien establecido para la toxoplasmosis congénita ha sido informado en un país europeo con bajaprevalencia1; Sin embargo, este programa también tiene sido implementado en países con menoringresos, pero con un mayor porcentaje de recién nacidos niños infectados. Llevamos a cabo un estudio en 11 hospitales comunitarios de salud pública en el Departamento de Quindio, excluyendo la capital (Armenia), en Colombia; alrededor de 4560 niños se entregan en estos hospitales anualmente.Bebés nacidos de agosto de 2003 a diciembre2003 se inscribieron en el estudio. Informadoel consentimiento se obtuvo de las madres durante el muestreo y los resultados se informaron de acuerdo con la resolución 008430 de 1993 de Ministerio de Salud Pública sobreinvestigación médica en Colombia. Todo el suero
