Resumen
- Purpose: To analyze the etiology, clinical characteristics, complications, treatments and outcomes of patients with intermediate uveitis examined at a uveitis referral center in Bogotá, Colombia. Patients and Methods: A retrospective descriptive study was performed. Medical records of patients attending a uveitis referral center in Bogotá, Colombia, between 2013 and 2020 were systematically reviewed. Data analysis included demographics, etiology, clinical characteristics, treatment modalities, best-corrected visual acuity, and complications. Absolute and relative frequencies were used for categorical variables, while means and standard deviations were calculated for continuous variables. Results: Eighteen patients with intermediate uveitis were identified. The mean age at disease onset was 19.4 years. There was no gender predominance. Two thirds of the patients had bilateral involvement. Mean initial best-corrected visual acuity was 0.19 LogMAR. The most frequent etiology was idiopathic, followed by undetermined, tuberculosis, multiple sclerosis and juvenile idiopathic arthritis. The most common features were insidious onset, chronic course and persistent duration. Complications encountered were macular edema, optic disc edema, cataract, epiretinal membrane, among others. Corticosteroids and immunosuppressive therapy were the most common treatments.
- Purpose: To analyze the etiology, clinical characteristics, complications, treatments, and outcomes of patients with intermediate uveitis examined in a uveitis referral center in Bogotá, Colombia. Patients and Methods: We conducted a retrospective descriptive study. We reviewed systematically the clinical records of patients attending a uveitis referral center in Bogotá, Colombia from 2013 to 2020. Data analysis included demographics, etiology, clinical characteristics, treatment modalities, best-corrected visual acuity, and complications. For categorical variables, absolute and relative frequencies were used while for continuous variables mean and standard deviations were calculated. Results: We identified 18 patients with intermediate uveitis. The mean age at disease onset was 19.4 years. There was no sex predominance. Two-thirds of the patients presented bilateral involvement. The mean initial best-corrected visual acuity was 0.19 LogMAR. The most common etiology was idiopathic followed by undetermined, tuberculosis, multiple sclerosis, and juvenile idiopathic arthritis. The most common characteristics were insidious onset, chronic course, and persistent duration. The complications found were macular edema, optic disk edema, cataract, epiretinal membrane, among others. Corticosteroids and immu-nosuppressive therapy were the most common treatments. Mean follow-up time was 24.4 months, and the mean final best-corrected visual acuity was 0.12 LogMAR. Conclusion: This is the first study describing intermediate uveitis features in South America. In our context, intermediate uveitis is infrequent. Polyautoimmunity and familial autoimmunity phenomena were found in some patients. These may require a multidisciplinary approach. Ophthalmologists should promptly diagnose, treat, and refer patients with this disease to avoid common complications. Further studies are required to determine the disease relation with polyautoimmunity.