Purpose: To describe the clinical presentation of Vogt-Koyanagi-Harada syndrome in a group of patients in Colombia. Methods: Retrospective-review of 2638 medical-records of patients with uveitis in two centers during 17 years. Results: Twenty-five patients with uveitis were diagnosed with Vogt-Koyanagi-Harada syndrome (0. 95%), 23 patients were included in the data analysis (0. 87%), 78. 3% females, mean age of diagnosis 37 years old (SD ±29). Main complaints: blurred vision (87%), headaches (47. 8%), tinnitus (26. 1%) and hearing impairments (21. 7%). Ophthalmic findings: bilateral serous retinal-detachment (73. 9%), non-granulomatous uveitis (52. 3%). Most of the patients were diagnosed with probable disease (56. 5%). Mean duration of follow-up was fourteen months; disease relapse was encountered in 26% of patients despite treatment. Conclusion: Patients in Colombia with Vogt-Koyanagi-Harada had clinical features similar to those reported in other Hispanic populations, except for the non-granulomatous uveitis. This disease may be considered as having variation of clinical manifestations across population groups.
